$4450
$3560
The regenerative dentistry market size is projected to reach US$ 4.72 billion by 2031 from US$ 2.32 billion in 2024. The market is expected to register a CAGR of 10.8% during 2025–2031. Increased adoption of tissue regeneration is likely to bring new market trends during the forecast period.
Regenerative Dentistry Market Analysis
As people age, they are more likely to encounter dental issues, including tooth loss, which increases the demand for dental procedures, including regenerative dentistry. According to the WHO facts published in October 2022, one in six individuals worldwide will be aged 60 or over by 2030. By then, the number of people aged 60 and above will increase from 1 billion in 2020 to 1.4 billion. The population of people aged 60 years and above will quadruple to 2.1 billion by 2050. It is anticipated that the population of those aged 80 or older will triple between 2020 and 2050, reaching 426 million. The rate of gum disease increases with age, and adults aged 65 years and above have some form of gum disease. As per the Centers for Disease Control and Prevention, in the US, ~70.1% of adults over the age of 65 had periodontal disease in 2020.
According to global estimates, the prevalence of edentulism (complete tooth loss) among individuals aged 65–74 is as high as 35% in upper-middle-income countries. In contrast, low-income countries report a lower prevalence (10%), highlighting disparities in access to preventive and restorative dental care. Beyond aging populations, vulnerable groups such as homeless individuals experience a disproportionately high burden of oral diseases. A study on homeless patients by European Review for Medical and Pharmacological Sciences found that 25.45% suffered from edentulism or missing teeth. Also, 80% reported acute tooth pain. The lack of access to early dental intervention in such groups necessitates regenerative solutions that can restore lost dental structures and improve quality of life. Also, advancements in regenerative dental treatments, such as biomaterials and stem cell therapies, accelerate global market growth.
Regenerative Dentistry Market Overview
The regenerative dentistry market is expanding due to the rising prevalence of dental disorders, soaring aging population, and surging demand for cosmetic dentistry. Prominent players operating in the market are focusing on innovation and collaboration for enhanced product availability. However, the high-cost barriers in dental regeneration treatment hinder the regenerative dentistry market growth. Market players in regenerative dentistry can capitalize on rising demand for biomaterials, minimally invasive solutions, and digital integration, which is driven by aging populations and cosmetic dentistry trends are providing opportunities in the regenerative dentistry market growth.
Customize Research To Suit Your Requirement
We can optimize and tailor the analysis and scope which is unmet through our standard offerings. This flexibility will help you gain the exact information needed for your business planning and decision making.
Regenerative Dentistry Market: Strategic Insights
Mrinal
Have a question?
Mrinal will walk you through a 15-minute call to present the report’s content and answer all queries if you have any.
Speak to Analyst
Customize Research To Suit Your Requirement
We can optimize and tailor the analysis and scope which is unmet through our standard offerings. This flexibility will help you gain the exact information needed for your business planning and decision making.
Regenerative Dentistry Market: Strategic Insights
Mrinal
Have a question?
Mrinal will walk you through a 15-minute call to present the report’s content and answer all queries if you have any.
Speak to Analyst
Regenerative Dentistry Market Drivers and Opportunities
Surging Demand for Cosmetic Dentistry
The increasing demand for cosmetic dentistry is driving the growth of the regenerative dentistry market. A rising number of patients seek procedures such as dental implants, veneers, and gum contouring to enhance their smiles. This trend is fueled by rising disposable incomes, social media influence, and advancements in minimally invasive techniques.
Europe, along with the Americas, hosts a significant portion of the global dental workforce, with 69% of the world’s 1.6 million dentists serving only 27% of the global population. This concentration of skilled dental professionals ensures that European patients have better access to advanced cosmetic and regenerative treatments than other regions. Meanwhile, Africa, with only 1% of the global dental workforce, faces challenges in meeting oral health needs. The availability of cutting-edge regenerative solutions in Europe—such as stem cell therapy and biomaterial implants—caters to functional and aesthetic demands.
In recent years, an increasing number of people have sought to have teeth that are straight and free of chips or other noticeable imperfections. Dentists have responded to these consumer demands, offering cosmetic procedures, such as implants and veneers. Baby boomers and millennials are the primary contributors to the growth of the cosmetic dentistry industry. Dental implants are commonly used in the dental treatments of older populations. However, the share of the younger population who are opting for dental implantation methods instead of bridges is rising. Aside from restoring teeth functions, dental implants favor the inclination of people toward natural-looking teeth that can last as long as regular teeth, improve a person's physical appearance, and provide comfort and convenience, unlike removable dentures. Dental cosmetic surgeries are among the most familiar cosmetic procedures worldwide due to their easy accessibility and practicality.
With ongoing advancements in research and greater awareness of regenerative options, the demand for these treatments is surging, benefiting practitioners and patients seeking superior aesthetic results.
Technological Advancements
Technological advancements are creating significant opportunities in the regenerative dentistry market, revolutionizing dental procedures and enhancing patient outcomes. Here are key innovations driving the transformation:
- 3D Printing and Bioprinting:
Customized Implants and Prosthetics: 3D printing technology allows for the creation of patient-specific dental implants and prosthetics. Clinics and labs are adopting 3D bioprinting to produce customized dental crowns, bridges, and implants with high precision. This trend enhances the fit and appearance while reducing surgery time and improving success rates. Companies such as Stratasys are already providing dental-specific 3D printers, creating opportunities for greater personalization in treatments. Clinics such as DentalPro have begun using 3D-printed bone grafts, enabling personalized treatment plans that align closely with individual patient needs.
• Stem Cell Therapy for Tooth Regeneration:
Dental Pulp and Bone Regeneration: Researchers are exploring the potential of dental stem cells for regenerating dental tissues. Stem cells derived from oral tissues, such as dental pulp and periodontal ligaments, are being investigated for their ability to regenerate damaged tissues and even whole teeth. Products, including Tooth Bank's Dental Stem Cells, launched in 2022, facilitate the collection and preservation of stem cells from extracted teeth. They provide valuable biological material for future regenerative procedures.
• Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF):
Enhanced Healing and Regeneration: PRP and PRF are adopted in Italy for soft tissue regeneration and bone healing. These treatments utilize a patient's platelets to stimulate faster healing after surgery and improve implant integration. Italian clinics are incorporating these therapies in procedures such as periodontal regeneration and implant surgeries. These procedures provide a minimally invasive and highly effective option for patients. Clinics such as Clinica Dental Mimmo are integrating PRP treatments into bone grafting procedures, significantly enhancing patient recovery times.
• Regenerative Materials:
Innovations in biomaterials, such as bioactive glass and hydroxyapatite composites, have improved the efficacy of grafts. Introduction of OsseoSpeed TRX implants by Dentsply Sirona has provided dentists with advanced solutions that promote osseointegration and support faster recovery.
• Integration of Artificial Intelligence (AI):
The incorporation of AI, particularly machine learning and deep learning, has transformed diagnostics, treatment planning, and regenerative procedures in dentistry. AI algorithms analyze extensive datasets to identify patterns and make informed decisions, enhancing the precision and efficiency of regenerative treatments.
• Tissue Engineering and Biomaterials:
Regenerative strategies that utilize scaffolds present opportunities to improve treatment options beyond the conventional repair methods used in root canal treatment (RCT) and vital pulp treatment (VPT). Scaffolds in regenerative medicine are usually three-dimensional (3D) porous biomaterials designed to provide structural support for regenerative processes and to facilitate the delivery of cells and/or bioactive agents.
These advancements are creating new opportunities for dental practitioners and businesses, enhancing the quality of care while enabling patient-specific treatments.
Regenerative Dentistry Market Report Segmentation Analysis
Key segments that contributed to the derivation of the regenerative dentistry market analysis are type, technology, application, age group, and end user.
- Based on type, the regenerative dentistry market is segmented into natural biomaterials and synthetic biomaterials. The natural biomaterials segment held the largest share of the market in 2024.
- By technology, the market is divided into tissue engineering, stem cell therapy, and others. The tissue engineering segment held the largest share of the market in 2024.
- Per application, the regenerative dentistry market is categorized into periodontal regeneration, endodontic regeneration, tooth reconstruction, bone regeneration, and others. The periodontal regeneration segment held the largest share of the market in 2024.
- Based on age group, the regenerative dentistry market is bifurcated into pediatric and adult. The adult segment held a larger share of the market in 2024.
- By end user, the regenerative dentistry market is categorized into hospitals, dental clinics, and others. The dental clinics segment dominated the market in 2024.
Regenerative Dentistry Market Share Analysis by Geography
The geographic scope of the regenerative dentistry market report mainly focuses on five regions: North America, Asia Pacific, Europe, South & Central America, and the Middle East & Africa. In terms of revenue, North America dominated the market in 2024. It is expected to continue its dominance in the global market during the forecast period. The US is the largest market for regenerative dentistry in the world. Cavities and gum disease are among the most preventable public health challenges in the US. According to the CDC, more than 90% of adults aged 20 to 64 have experienced at least one cavity in their lifetime. Nearly 21% of this same age group had one or more untreated decayed permanent teeth in 2024. The situation is concerning among children, with more than half (52%) of those aged 6 to 8 having encountered cavities in their primary teeth. Additionally, nearly 47% of adults aged 30 and older exhibit signs of gum disease, a condition that becomes more common as individuals age. As per the American Dental Association (2020), ~5 million people aged 65–74 are edentulous in the country.
The adoption of stem cell therapies and tissue engineering in regenerative dentistry in the US is transforming how dentists approach tooth repair, tissue regeneration, and the possibilities of whole-tooth engineering. Phase I and II clinical trials conducted in the US and internationally have shown the safety and initial effectiveness of stem cell-based dental regenerative procedures. However, many of these studies involve small sample sizes and have short follow-up periods. It highlights the necessity for larger, multicenter trials. Studies involving autologous dental pulp stem cells (DPSCs) combined with collagen scaffolds have reported positive pulp vitality responses and radiographic evidence of root maturation in immature permanent teeth. Likewise, clinical applications of SCAP-loaded hydrogels have demonstrated revascularization and apical closure in necrotic teeth. Thus, the increasing incidence of oral diseases and ongoing research initiatives are promoting the adoption of regenerative technologies in the US.
Regenerative Dentistry Market Report Scope
Regenerative Dentistry Market News and Recent Developments
The regenerative dentistry market is evaluated by gathering qualitative and quantitative data post primary and secondary research. This data includes important corporate publications, association data, and databases. Key developments witnessed in the regenerative dentistry market:
- Geistlich received MDR (Medical Device Regulation) certification for its established Chondro-Gide collagen membrane from the notified body TÜV SÜD Product Service GmbH. This approval ensures that the collagen membrane in orthopaedics continues to benefit patients in Europe. (Source: Geistlich, Press Release, July 2024)
- BioHorizons Camlog announced the launch of Striate+, an innovative collagen membrane developed by Orthocell for advanced bone and tissue regeneration. Both companies have entered into a global distribution and manufacturing agreement for Striate+. (Source: BioHorizons Camlog, Press Release, February 2024)
Regenerative Dentistry Market Report Coverage and Deliverables
The "Regenerative Dentistry Market Size and Forecast (2021–2031)" report provides a detailed analysis of the market covering below areas:
- Regenerative dentistry market size and forecast at the global, regional, and country levels for all the key market segments covered under the scope
- Regenerative dentistry market trends, as well as market dynamics such as drivers, restraints, and key opportunities
- Detailed PEST and SWOT analysis
- Regenerative dentistry market analysis covering key market trends, global and regional framework, major players, regulations, and recent market developments
- Industry landscape and competition analysis covering market concentration, heat map analysis, prominent players, and recent developments for the regenerative dentistry market
- Detailed company profiles
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
This text is related
to segments covered.
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
This text is related
to country scope.
Frequently Asked Questions
Dentsply Sirona, Geistlich Pharma AG, Evonik Industries AG, ZimVie Inc., BioHorizons, Inc., Nobel Biocare, UBGEN Srl, B. & B. Dental S.r.l, Botiss Biomaterials GmbH, and Envista Holdings Corporation are among the key players operating in the market.
The regenerative dentistry market value is expected to reach US$ 4.72 billion by 2031.
The rising prevalence of dental disorders, soaring aging population, and surging demand for cosmetic dentistry are among the significant factors fueling the market growth.
North America dominated the regenerative dentistry market in 2024.
The increased adoption of tissue regeneration is likely to emerge as a new trend in the market in the coming years.
The market is expected to register a CAGR of 10.8% during 2025–2031.
The List of Companies - Regenerative Dentistry Market
- Dentsply Sirona Inc
- Geistlich Pharma AG
- Evonik Industries AG
- ZimVie Inc.
- BioHorizons Inc.
- Nobel Biocare Services AG
- UBGEN
- B&B Dental Implant Company
- Botiss Biomaterials GmbH
- Envista Holdings Corporation
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
Trends and growth analysis reports related to Regenerative Dentistry Market
Jul 2025
Infectious Disease In vitro Diagnostics Market
Size and Forecast (2021-2031), Global and Regional Share, Trend, and Growth Opportunity Analysis Report Coverage: Application (HIV or AIDS, Tuberculosis, Hepatitis B and C, Malaria, and Others), End User (Hospitals and Clinics, Diagnostic Laboratories, Blood Bank, and Others), and Geography
Jul 2025
Donor Blood Components Market
Size and Forecast (2021–2031), Global and Regional Share, Trend, and Growth Opportunity Analysis Report Coverage: Blood Component (Red Blood Cells, White Blood Cells, Platelets, Plasma, and Others), Indication (Immunosuppression and Oncology), Application (Anemia Management, Thrombocytopenia Treatment, Coagulopathy Correction, Supportive Care During Chemotherapy, Surgery, and Others), Age Group (Adult and Child), End User (Hospitals, Oncology Centers, Transplant Centers, Ambulatory Surgical Centers, and Others), and Geography
Jul 2025
Aesthetic Injectable Devices Market
Size and Forecast (2021-2031), Global and Regional Share, Trend, and Growth Opportunity Analysis Report Coverage: Product (Dermal Filler, Botulinum Toxin and Others), Dermal Fillers (Calcium Hydroxylapatite, Hyaluronic Acid, Collagen, Poly-L-Lactic Acid, Polymethylmethacrylate, Fat Fillers, and Others), Device Type (Microcannulas, Pre-Filled Syringes, Mesotherapy Guns, and Others), Application (Facial Line Correction, Face Lift, Lip Treatment, Anti-Ageing and Wrinkle Treatment, Acne and Scar Treatment, Stretch Marks, and Others), Age Group (Up to 30, 31-40, 41-50, 51-60, and More Than 60), Gender (Female and Male), End User (Medical Spas, Dermatology Clinics, Hospitals, and Others), and Geography
Jul 2025
ECG Monitoring Equipment Market
Size and Forecast (2021-2031), Global and Regional Share, Trend, and Growth Opportunity Analysis Report Coverage: By Product (Resting ECG, Stress ECG, Holter Monitors, and Cardiopulmonary Stress Testing Monitors), Lead Type (12-Lead ECG, 3–6 Lead ECG, and Single Lead), Technology [Portable (Wired) ECG System and Wireless ECG System], End User (Hospital and Clinics, Ambulatory Surgical Centers, Cardiac Centers, and Others), and Geography (North America, Europe, Asia Pacific, Middle East & Africa, and South & Central America)
Jul 2025
Prescription Drugs Market
Size and Forecast (2021-2031), Global and Regional Share, Trend, and Growth Opportunity Analysis Report Coverage: Product Type (Branded and Generics), Drug Type (Small Molecule and Biologics and Biosimilar), Therapeutic Area (Oncology, Cardiovascular Diseases, Neurological Diseases, Metabolic Diseases, Respiratory Diseases, Immunology, and Others), Route Of Administration (Oral, Injectable, Topical, and Others), Distribution Channel (Hospital Pharmacies, Retail Pharmacies and Online Pharmacies), and Geography (North America, Europe, Asia Pacific, Middle East & Africa, and South & Central America)
Jul 2025
Regenerative Dentistry Market
Size and Forecast (2021 - 2031), Global and Regional Share, Trend, and Growth Opportunity Analysis Report Coverage: By Type (Natural and Synthetic), Technology (Tissue Engineering, Stem Cell Therapy, and Others), Application (Periodontal Regeneration, Endodontic Regeneration, Tooth Reconstruction, Bone Regeneration, and Others), Age Group (Adult and Pediatric), End User (Dental Clinics, Hospital, and Others), and Geography
Jul 2025
Wound Closure Devices Market
Size and Forecast (2021 - 2031), Global and Regional Share, Trend, and Growth Opportunity Analysis Report Coverage: By Product (Sutures, Adhesives, Staplers, Strips, and Others), Wound Type (Chronic Wound and Acute Wound), End User (Hospitals, Clinics, Ambulatory Surgery Centers, and Others), and Geography
Jul 2025
Cell and Gene Therapy Contract Development and Manufacturing Organization Market
Size and Forecast (2021 - 2031), Global and Regional Share, Trend, and Growth Opportunity Analysis Report Coverage: By Service Type (Drug Development and Manufacturing, Testing and Regulatory Services, and Others), Product Type (Gene Therapy and Cell Therapy), End User (Pharmaceutical Companies, Biopharmaceutical Companies, and Others), and Geography