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The Chronic Total Occlusion market size is projected to reach US$ 4.22 billion by 2031 from US$ 2.44 billion in 2024. The market is expected to register a CAGR of 8.2% during 2025–2031.
Chronic Total Occlusion Market Analysis
The rising geriatric population is a key driver for the chronic total occlusion (CTO) market. As the world population grows older, cardiovascular diseases become more common. According to the US Census Bureau, the number of Americans aged 65 and above is expected to increase from 58 million in 2022 to 82 million by 2050, which is a 47% increase. The percentage of the population aged 65 and older is expected to increase from 17% to 23% by 2050. According to Statistics Canada, in 2022, around one in five Canadians (18.8% of the population; 7,329,910 people) were at least 65 years of age.
Older adults, particularly those over 60 years of age, are at higher risk of cardiovascular diseases due to age-related changes in the cardiovascular system, such as decreased blood vessel elasticity and arterial plaque. The growing elderly population worldwide is driving the need for efficient and minimally invasive treatments, such as percutaneous coronary intervention (PCI) for chronic total occlusion (CTO). Older adults often struggle to adjust to traditional surgical methods, which is why there is a rising preference for minimally invasive procedures that promote faster recovery and reduce risk. This is a phenomenon that can be seen in countries with high aging populations, such as the US, Japan, and European nations.
Chronic Total Occlusion Market Overview
The chronic total occlusion market in North America is divided into the US, Canada, and Mexico. North America accounts for a significant share of the global chronic total occlusion market. The market in this region is influenced by the increasing aging population and the surging cardiovascular disease (CVD) prevalence, especially coronary artery disease (CAD). According to the 2023 Profile of Older Americans, in 2022, there were 57.8 million adults aged 65 or more in the US, including 31.9 million women and 25.9 million men. The same report also stated that heart disease remains the number one cause of death in all Americans, affecting people of all ages and particularly harming those aged 75 and above (24.1%). Technological innovations, including percutaneous coronary interventions (PCI) and dedicated chronic total occlusion (CTO) devices, enabling minimally invasive procedures, are the major drivers of the demand for CTO procedures. Medtronic, Boston Scientific, and Abbott Laboratories are the key players in the market, which emphasize on creating innovative devices for CTO interventions. The US also has a high rate of adoption of these technologies because of the developed healthcare system and favorable reimbursement policies. The increasing awareness of early detection and treatment of CVDs is a major growth opportunity. In addition, growth in specialized centers and cardiology departments contributes to the enhanced availability of CTO procedures in the region.
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Chronic Total Occlusion Market: Strategic Insights
Market Size Value in US$ 280.7 Million in 2017 Market Size Value by US$ 516.1 Million by 2025 Growth rate CAGR of 8.1% from 2018-2025 Forecast Period 2018-2025 Base Year 2018
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Chronic Total Occlusion Market Drivers and Opportunities
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Chronic Total Occlusion Market: Strategic Insights
| Market Size Value in | US$ 280.7 Million in 2017 |
| Market Size Value by | US$ 516.1 Million by 2025 |
| Growth rate | CAGR of 8.1% from 2018-2025 |
| Forecast Period | 2018-2025 |
| Base Year | 2018 |
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Market Drivers:
Advancements in CTO PCI Techniques and Devices:
Development of specialized wires, microcatheters, and re-entry devices with improved success ratesand safety profileRising Prevalence of Coronary Artery Disease:
Aging population and increasing rates of diabetes, hypertension, and obesity lead to more complex coronary lesions, including CTOs. Many patients with stable CAD have at least one CTO.Growing Evidence of Clinical Benefits:
Studies have shown potential improvement in angina relief, quality of life, and left ventricular function in selected patients. Improved imaging and physiology tools support patient selection
Market Opportunities:
Expanding Operator Training and Access:
CTO PCI remains technically challenging; more operators need structured training and proctorship. Opportunity to develop dedicated CTO centers of excellence.Improved Patient Identification and Referral Pathways:
Many CTOs are underdiagnosed or not referred for PCI due to outdated perceptions of futility or risk. Leveraging non-invasive imaging (CT angiography) and AI tools can help identify suitable candidates.Innovation in Technology and Imaging:
Ongoing development of AI-guided navigation, robotics, and real-time 3D imaging. Potential for shorter procedures, reduced radiation exposure, and increased success in complex cases.
Chronic Total Occlusion Market Report Segmentation Analysis
The chronic total occlusions market is divided into different segments to give a clearer view of how it works, its growth potential, and the latest trends. Below is the standard segmentation approach used in most industry reports:
By Equipment:
Guide Wire:
As a critical element of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) procedures, guidewires enable physicians to navigate through complex, blocked coronary arteries, enabling lifesaving treatments such as stent implantation, balloon angioplasty, and other therapeutic interventions.Micro Catheters:
The market for CTO devices is primarily driven by microcatheters, as they enable minimally invasive procedures. These procedures decrease the necessity for more invasive surgical options, such as coronary artery bypass grafting (CABG). As a result, there is a growing preference for CTO PCI techniques over traditional surgery, leading to increased demand for microcatheters.Crossing Devices:
Crossing devices are essential tools in CTO PCI, with a central role in navigating and crossing challenging and totally blocked coronary arteries. Crossing devices are developed to assist interventional cardiologists in crossing the occlusion to allow for the following treatment, e.g., balloon angioplasty or stenting. With the increasing number of CTO procedures, the market for crossing devices also continues to expand.Re-Entry Devices:
Re-entry devices are the key elements in the CTO devices market that are specifically developed to allow re-entry into the true lumen of coronary arteries following a successful subintimal crossing. These devices are applied when interventional cardiologists are unable to cross an occlusion through the normal route, causing a dissection of the artery wall. Re-entry devices permit the re-establishment of the guidewire or catheter into the proper course, greatly enhancing procedure success rates. With CTO procedures on the rise all over the world, re-entry devices are becoming an integral component of PCI.Others:
The growth of the chronic total occlusion (CTO) devices market is significantly influenced by the advancements in sheaths, snares, and balloon devices. These tools are essential in facilitating the complex navigation and intervention required for successful revascularization of occluded arteries. Sheaths provide support and access for other devices, snares aid in retrieving occluded material or crossing lesions, and balloon devices are crucial for dilating blockages.
By End User:
- Hospitals
- Ambulatory Care Centers
- Others
By Geography:
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East & Africa
The chronic total occlusions market in North America is expected to hold a significant share of the market. The the increasing aging population and the surging cardiovascular disease (CVD) prevalence, especially coronary artery disease (CAD) are factors likely to drive the market.
Chronic Total Occlusion Market Report ScopeChronic Total Occlusion Market Share Analysis by Geography
Asia Pacific is expected to grow the fastest in the next few years. Emerging markets in Latin America, the Middle East, and Africa also have many untapped opportunities for chronic total occlusion providers to expand.
The chronic total occlusions market grows differently in each region. This is because of factors such as growing demand for minimally invasive procedures, coupled with the rising elderly population and CVD infection rate. Below is a summary of market share and trends by region:
1. North America
Market Share:
Holds a significant portion of the global marketKey Drivers:
- High prevalence of coronary artery disease
- Advanced healthcare infrastructure and favorable reimbursement environment
- Ongoing R and D and technological innovation
Trends:
Increasing launches and adoption of advanced devices
2. Europe
Market Share:
Substantial share due to the increasing prevalence of ENT diseasesKey Drivers:
- Regulatory acceleration and updated guidelines
- High CAD incidence with aging populations and unhealthy lifestyle trends
- Evolution of procedural techniques and devices
Trends:
Advances in Guidewire and Imaging Technology
3. Asia Pacific
Market Share:
Fastest-growing region with a rising market share every yearKey Drivers:
- Rapidly growing cardiovascular disease burden and aging population
- Healthcare investment and infrastructure expansion
- Technology adoption and growth potential
Trends:
Improved awareness, minimally invasive procedure adoption, and broader access to sophisticated CTO devices
4. South and Central America
Market Share:
Growing market with steady progressKey Drivers:
- Emerging healthcare infrastructure growth
- Increasing disease prevalence tied to lifestyle shifts
- Expansion of minimally invasive treatment access
Trends:
Expansion likely as treatment awareness and accessibility improve.
5. Middle East and Africa
Market Share:
Although small, but growing quicklyKey Drivers:
- Growing healthcare infrastructure and accessibility
- Rising cardiovascular disease incidence
- Technology diffusion from global markets
Trends:
As public health systems mature and emerging specialized cardiac centers increasing adoption of CTO
Chronic Total Occlusion Market Players Density: Understanding Its Impact on Business Dynamics
High Market Density and Competition
Competition is strong due to the presence of established players such as Asahi Intecc Co Ltd, Cordis Corp, Integer Holdings Corp, Boston Scientific Corp, Becton Dickinson and Co, SoundBite Medical Solutions, Medtronic Plc, Terumo Corp, Abbott, and Koninklijke Philips NV.
This high level of competition urges companies to stand out by offering:
- Advanced Products
- Value-added services such as customization and sustainable solutions
- Competitive pricing models
- Compliance with regulatory guidelines
Opportunities and Strategic Moves
- Major market players such as Medtronic, Abbott, Boston Scientific, Cardinal Health, and Becton Dickinson have expanded its product portfolios through acquisitions and collaborations, especially in advanced device segments such as re-entry systems and atherectomy devices. Strategic planning around scalable production, supplier qualification, and risk management are essential to maintain cost competitiveness and supply reliability for new CTO device launches.
- There is rapid development in guidewires, microcatheters, re-entry devices, and imaging modalities to improve procedural success and safety. Innovations like real-time fusion imaging and robotics will drive future market expansion and differentiation
- Companies excel by bundling CTO devices with other endovascular offerings to provide comprehensive solutions to healthcare providers. Strategic planning around scalable production, supplier qualification, and risk management are essential to maintain cost competitiveness and supply reliability for new CTO device launches.
Major Companies operating in the Chronic Total Occlusion Market are:
- Asahi Intecc Co Ltd
- Cordis Corp
- Integer Holdings Corp
- Boston Scientific Corp
- Becton Dickinson and Co
- SoundBite Medical Solutions
- Medtronic Plc
- Terumo Corp
- Abbott
- Koninklijke Philips NV
Disclaimer: The companies listed above are not ranked in any particular order.
Other companies analysed during the course of research:
- Baylis Medical Company, Inc
- SPECTRANETICS, C. R. Bard, Inc.
- IntraLuminal Therapeutics
- Acrostak Int. Distr. Sarl
- Cardinal Health
- Cook Medical
- Merit Medical Systems
- Penumbra, Inc.
- Reflow Medical
- Teleflex Incorporated
- Infraredx, Inc.
- Vascular Solutions, Inc.
- Acrostak Corporation
- AngioDynamics, Inc.
- Biotronik SE & Co. KG
- Biosensors International Group, Ltd.
- Philips Healthcare
- Boston Scientific Corporation
Chronic Total Occlusion Market News and Recent Developments
Integer to Showcase Leadership in Medical Device Innovation and Recent Acquisition of Precision Coating at MD and M West 2025
Integer Holdings exhibited at MD&M West 2025 from February 4-6 at the Anaheim Convention Center, showcasing their medical device manufacturing capabilities. The company demonstrated their expertise in cardio and vascular solutions, cardiac rhythm management, and neuromodulation products, including their global rapid prototyping services with two-week turnarounds..Philips announces 1500+ Cath Lab installations in the Indian Subcontinent Royal Philips announced at India Live 2024 in New Delhi that it had completed over 1,500 Cath Lab (interventional suite) installations in the Indian Subcontinent. The completion of these 1,500+ Cath Lab installations marked a significant milestone in Philips’ mission to create innovative solutions aimed at achieving the company’s Quadruple Aim of better health outcomes, improved patient experience, enhanced staff experience, and lower cost of care. At the event, Philips also announced the launch of two groundbreaking products to address the burden of cardiovascular disease in India.
Chronic Total Occlusion Market Report Coverage and Deliverables
The "Chronic Total Occlusion Market Size and Forecast (2021–2031)" report provides a detailed analysis of the market covering below areas:
- Chronic Total Occlusion Market size and forecast at global, regional, and country levels for all the key market segments covered under the scope
- Chronic Total Occlusion Market trends, as well as market dynamics such as drivers, restraints, and key opportunities
- Detailed PEST and SWOT analysis
- Chronic Total Occlusion Market analysis covering key market trends, global and regional framework, major players, regulations, and recent market developments
- Industry landscape and competition analysis covering market concentration, heat map analysis, prominent players, and recent developments for the Chronic Total Occlusion Market
- Detailed company profiles
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
Equipment ; End User and Geography
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
US, Canada, Mexico, UK, Germany, Spain, Italy, France, India, China, Japan, South Korea, Australia, UAE, Saudi Arabia, South Africa, Brazil, Argentina
Frequently Asked Questions
The chronic total occlusions market is estimated to register a CAGR of 8.2% during the forecast period.
The increasing aging population and the rising prevalence of cardiovascular diseases are among the factors contributing to market growth.
Asahi Intecc Co Ltd, Cordis Corp, Integer Holdings Corp, Boston Scientific Corp, Becton Dickinson and Co, SoundBite Medical Solutions, Medtronic Plc, Terumo Corp, Abbott, and Koninklijke Philips NV are among the key players operating in the chronic total occlusions market.
The chronic total occlusions market is estimated to reach US$ 4.22 Billion by 2031.
North America dominated the market in 2024.
The List of Companies - Chronic Total Occlusion Market
- Asahi Intecc Co Ltd
- Cordis Corp
- Integer Holdings Corp
- Boston Scientific Corp
- Becton Dickinson and Co
- SoundBite Medical Solutions
- Medtronic Plc
- Terumo Corp
- Abbott
- Koninklijke Philips NV
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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