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The Nonsteroidal Anti-inflammatory Drugs (NSAID) market size is projected to reach US$ 38.38 billion by 2031 from US$ 24.82 billion in 2024. The market is expected to register a CAGR of 6.5% during 2025–2031.
Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Analysis
The surging prevalence of chronic pain disorders and inflammatory conditions such as arthritis and headaches, and the growing adoption of non-opioid NSAIDs, are propelling the growth of the nonsteroidal anti-inflammatory drugs (NSAID) market. The introduction of NSAIDs offers an efficient approach for the treatment of pain and inflammation. In response to the growing burden of chronic pain, pharmaceutical companies are introducing new NSAID formulations to meet patient needs.
The increasing strategic initiatives by manufacturers of NSAIDs present a significant market opportunity. They are a major factor contributing to the growth of nonsteroidal anti-inflammatory drugs (NSAIDs).
Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Overview
The global market for Nonsteroidal Anti-Inflammatory Drugs is expected to grow steadily in the coming years. An increase in chronic pain, inflammatory disorders, and an aging population fuels this growth.
NSAIDs can be classified by their chemical structure and their selectivity for COX enzymes. Some are nonselective, affecting both COX-1 and COX-2, while others are selective for COX-2. These drugs are a group of medications that reduce pain, fever, and inflammation. They commonly treat conditions such as arthritis, muscle pain, and menstrual cramps.
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Nonsteroidal Anti-Inflammatory Drugs (NSAID) Market: Strategic Insights
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Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Drivers and Opportunities
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Nonsteroidal Anti-Inflammatory Drugs (NSAID) Market: Strategic Insights


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Market Drivers:
Expanding Preference for NSAIDs as Non-Opioid Pain Management:
NSAIDs are increasingly recognized for effectively alleviating pain while reducing the risk of dependency and side effects commonly linked to opioids. As a result, more patients and providers are turning to these medications to address pain more safely and sustainably.Increasing Prevalence Of Chronic and Inflammatory Diseases:
The introduction of NSAIDs offers an efficient approach for the treatment of pain and inflammation-causing disorders such as headaches, osteoarthritis, muscle and joint injuries, and various neuropathies.Rising Aging Population:
Aging populations in countries such as Japan, China, and South Korea contribute further, as elderly individuals are more prone to these ailments.
Market Opportunities:
Expansion in Emerging Economies:
Several countries in Asia Pacific, Latin America, and Africa offer growth opportunities in the nonsteroidal anti-inflammatory drugs (NSAID) market due to the increasing number of chronic infections and adoption of non-opioid pain management.Rising Strategic Initiatives:
Increasing organic and inorganic initiatives, such as new product launches and geographical expansion by market players, offer lucrative opportunities for market size expansion.
Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Report Segmentation Analysis
The nonsteroidal anti-inflammatory drugs (NSAID) market is divided into different segments to give a clearer view of how it works, its growth potential, and the latest trends. Below is the standard segmentation approach used in most industry reports:
By Drug Class:
Nonselective NSAIDs:
Nonselective COX-2 inhibitors, including ibuprofen and naproxen, effectively reduce pain and inflammation by inhibiting both COX-1 and COX-2 enzymes. These drugs are increasingly in demand due to their broad-spectrum anti-inflammatory and analgesic effects.COX-2 Selective NSAIDs:
Selective COX-2 inhibitors, such as celecoxib (Celebrex) and etoricoxib, are designed to specifically block the enzyme cyclooxygenase-2 (COX-2), which is primarily responsible for producing prostaglandins that cause pain, inflammation, and fever during tissue injury.
By Route Of Administration:
Oral:
Oral NSAIDs can offer consistent systemic effects necessary for addressing widespread inflammation. Their efficacy, ease of use, and broad availability contribute to their increasing popularity.Injectable:
Injectable NSAIDs allow for shorter hospital stays and improved patient satisfaction by providing effective pain control early after surgery or trauma.Topical:
Patients and clinicians prefer topical NSAIDs to reduce systemic exposure and adverse events. Regulatory approvals of topical diclofenac formulations—such as gel 1%, patch 1.3%, and solution 1.5%—support this trend.
By Route Of Administration:
- Arthritis
- Migraine
- Ophthalmic Diseases
- Others
By Distribution Channel:
- Hospital Pharmacies
- Retail Pharmacies
- Online Channels
By Geography:
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East & Africa
The nonsteroidal anti-inflammatory drugs (NSAID) market in North America is expected to hold a significant share of the market.
Nonsteroidal Anti-Inflammatory Drugs (NSAID) Market Report ScopeNonsteroidal Anti-inflammatory Drugs (NSAID) Market Share Analysis by Geography
Asia Pacific is expected to grow the fastest in the next few years. Emerging economies such as Latin America, the Middle East, and Africa also have many untapped opportunities for nonsteroidal anti-inflammatory drug providers to expand.
The nonsteroidal anti-inflammatory drugs (NSAID) market grows differently in each region. This is because of factors including surging prevalence of inflammatory diseases, a growing aging population, and increasing business development initiatives by the market players. Below is a summary of market share and trends by region:
1. North America
Market Share:
Holds a significant portion of the global marketKey Drivers:
- Rise in musculoskeletal disorders, including arthritis.
- Increased awareness of the adverse effects of opioid painkillers
Trends:
Shift toward safer NSAID formulations with better gastrointestinal (GI) and cardiovascular profiles.
2. Europe
Market Share:
Substantial share due to the adoption of OTC NSAIDs.Key Drivers:
- Government support and favorable reimbursement policies.
- Growing awareness of migraines and other pain conditions.
Trends:
Technological advancements in drug delivery systems.
3. Asia Pacific
Market Share:
Fastest-growing region with a rising market share every yearKey Drivers:
- Increasing aging population.
- Growing demand for OTC NSAIDs
- Increasing disposable income
Trends:
Rise in medical tourism
4. South and Central America
Market Share:
Growing market with steady progressKey Drivers:
- Expanding access to healthcare services, particularly in urban areas
- Availability of essential drugs at subsidized rates
-
Trends:
Rise in medical tourism
5. Middle East and Africa
Market Share:
Although small, it is growing quicklyKey Drivers:
- Expanding Healthcare infrastructure
- Rising awareness about hygiene and infection control in healthcare settings
Trends:
Government initiatives supporting healthcare infrastructure.
Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Players Density: Understanding Its Impact on Business Dynamics
High Market Density and Competition
- Competition is strong due to the presence of established players such as Boehringer Ingelheim International GmbH, Hikma, and Novartis AG. Regional and niche providers like Pfizer (Asia Pacific) and Dr. Reddy's Laboratories Ltd (Asia Pacific) also add to the competitive landscape across different regions.
This high level of competition urges companies to stand out by offering:
- Advanced Products
- Value-added services like customization and sustainable solutions
- Competitive pricing models
- Compliance with regulatory guidelines
Opportunities and Strategic Moves
- Focusing on specialized gloves for sectors such as medical, food processing, industrial, and laboratory, featuring antimicrobial coatings and smart sensors for health monitoring.
- Companies are moving towards biodegradable and recyclable glove products to address regulatory and consumer concerns about plastic waste and environmental impact.
- Focusing on direct-to-consumer channels and enhancing the use of e-commerce platforms to reach a wider range of customer segments.
Major Companies operating in the Nonsteroidal Anti-inflammatory Drugs (NSAID) Market are:
- Pfizer
- Bayer AG
- Glenmark Pharmaceuticals Ltd.
- Dr. Reddy's Laboratories Ltd
- Boehringer Ingelheim International GmbH
- Haleon plc
- Sun Pharmaceutical Industries Ltd
- Novartis AG
- Hikma Pharmaceuticals
- Viatris Inc.
Disclaimer: The companies listed above are not ranked in any particular order.
Other companies analysed during the course of research:
- Teva Pharmaceutical Industries
- Mylan
- Aurobindo Pharma
- Actavis
- Wuxi AppTec
- Zhejiang NHU
- Johnson & Johnson (McNeil)
- Sanofi
- Reckitt Benckiser Group
- Horizon Therapeutics
- Assertio Holdings
- Perrigo Company
- AbbVie
- Endo International
- Orion Corporation
- Strides Pharma Science Limited
Nonsteroidal Anti-inflammatory Drugs (NSAID) Market News and Recent Developments
Boehringer Ingelheim BioXcellence is expanding its service portfolio in China
Boehringer Ingelheim's biopharmaceutical facility in Shanghai, China, meets the conditions required to participate in a regulatory reform promoting the segmented manufacturing of biological products by the local authorities.
Hikma Pharmaceuticals PLC (Hikma) launched Indomethacin suppositories in the US.
Hikma Pharmaceuticals PLC (Hikma), the multinational pharmaceutical company, launched Indomethacin Suppositories in the US in a 50mg dose. This product has been approved for marketing in the United States by the US FDA.
Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Report Coverage and Deliverables
The "Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Size and Forecast (2021–2031)" report provides a detailed analysis of the market covering below areas:
- Nonsteroidal Anti-inflammatory Drugs (NSAID) Market size and forecast at global, regional, and country levels for all the key market segments covered under the scope
- Nonsteroidal Anti-inflammatory Drugs (NSAID) Market trends, as well as market dynamics such as drivers, restraints, and key opportunities
- Detailed PEST and SWOT analysis
- Nonsteroidal Anti-inflammatory Drugs (NSAID) Market analysis covering key market trends, global and regional framework, major players, regulations, and recent market developments
- Industry landscape and competition analysis covering market concentration, heat map analysis, prominent players, and recent developments for the Nonsteroidal Anti-inflammatory Drugs (NSAID) Market
- Detailed company profiles

Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
This text is related
to segments covered.

Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
This text is related
to country scope.
Frequently Asked Questions
North America dominated the market in 2024.
The nonsteroidal anti-inflammatory drugs (NSAID) market is estimated to register a CAGR of 6.5% during the forecast period.
The nonsteroidal anti-inflammatory drugs (NSAID) market is estimated to reach US$38.38 billion by 2031.
The prevalence of chronic pain and inflammatory disorders, and growing inclination towards NSAIDs as the primary choice for non-opioid pain management are among the noteworthy factors contributing to the market growth.
The List of Companies - Non-steroidal Anti-inflammatory Drugs (NSAID) Market
- Pfizer
- Bayer AG
- Glenmark Pharmaceuticals Ltd.
- Dr. Reddy's Laboratories Ltd
- Boehringer Ingelheim International GmbH
- Haleon plc
- Sun Pharmaceutical Industries Ltd
- Novartis AG
- Hikma Pharmaceuticals
- Viatris Inc.
- Teva Pharmaceutical Industries
- Mylan
- Aurobindo Pharma
- Actavis
- Wuxi AppTec
- Zhejiang NHU
- Johnson & Johnson (McNeil)
- Sanofi
- Reckitt Benckiser Group
- Horizon Therapeutics
- Assertio Holdings
- Perrigo Company
- AbbVie
- Endo International
- Orion Corporation
- Strides Pharma Science Limited
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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